Los Angeles Headquarters (City) Association was initially established in 1961 by local commercial and business owners to actively promote the City of Los Angeles. As stated in its newsletter, “Los Angeles Headquarters Association is an organization of businesses committed to Los Angeles achieving its optimum potential as a major world city by fostering responsible economic growth and improving it quality of life.”

Activities of the association have included the "Adopt-A-School Program" and the "Save the Books Campaign," in response to the fire that severely damaged the Los Angeles Public Library. The Association has also sponsored several key annual awards banquets such as the Spirit of Los Angeles Award, Corporate Award, and Community Award. These awards are given to community leaders and businesses which have voluntary worked to promote the City of Los Angeles. The Association also sponsors forums to discuss economic and legislative issues effecting local businesses in Los Angeles, and publishes a quarterly newsletter, entitled, Focus.